(Time) – A new trial involving nearly 200 children with sickle-cell anemia found that monthly blood transfusions could reduce the chance of strokes by more than half in children who have the condition, according to U.S. News.
Sickle-cell anemia — a disorder in which red blood cells adopt a rigid, sickle shape that blocks flow, causing strokes and other complications — is most common in children of African and Central or South American descent. According to the U.S. National Heart, Lung and Blood Institute, 1 out of 500 African-American children in the U.S. is born with sickle-cell anemia. “Silent strokes” — which lack discernible symptoms but have also been known to reduce a child’s IQ — affect 30% of those with the condition.
Researchers involved in the study, published in the New England Journal of Medicine, used an MRI scan to identify 196 children ages 5 to 15 with a history of silent strokes, and gave about half of them monthly blood transfusions over three years. Out of the group that had monthly blood transfusions, only six had another stroke during the study, in comparison with 14 children in the control group who had another stroke.