(Business Standard) – Smoking can cause loss of the Y chromosome in blood cells, which may put male smokers at a greater risk of cancer, a new study has found. 

Researchers at Uppsala University in found an association between smoking and loss of the Y chromosome in blood cells. Loss of the Y chromosome was more common in heavy smokers compared to moderate smokers, the study found. 

Since only men have the Y chromosome, these might explain why smoking is a greater risk factor for among men and, in the broader perspective, also why men in general have a shorter life expectancy, researchers said. 

“We have previously in 2014 demonstrated an association between loss of the Y chromosome in blood and greater risk for cancer,” said Lars Forsberg, researcher at the Department of Immunology, Genetics and Pathology, Uppsala University.


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